Nuclear Magnetic Resonance (NMR) Spectroscopy

What is NMR Spectroscopy?

Nuclear Magnetic Resonance (NMR) Spectroscopy is a powerful analytical technique that uses magnetic fields and radiofrequency signals to determine molecular structure, purity, and chemical environment. By observing how atomic nuclei respond to magnetic excitation, NMR provides detailed information about chemical bonds, functional groups, molecular connectivity, and conformation.

Materials Metric supports multiple NMR nuclei including ¹H (proton), ¹³C (carbon), and ¹⁹F, along with advanced 2D experiments such as COSY, HSQC, and HMBC for in-depth structural elucidation of polymers, organic compounds, and biomolecules.

Use of NMR Spectroscopy

NMR is used to:
• Determine molecular structure and connectivity
• Confirm polymer composition and branching
• Identify impurities, degradation products, and side reactions
• Measure monomer ratios, functional group conversions, and end groups
• Evaluate biomolecules including peptides, metabolites, and natural compounds

Applications of NMR Spectroscopy

• Polymers: composition, crosslinking, additive identification
• Pharmaceuticals: purity, identity, stability testing
• Biomaterials: polymer chemistry and functionalization
• Organic Synthesis: structure verification and reaction monitoring
• Natural Products: metabolite and compound identification

Sample Analysis Process

1. Submission & Review

Identify nuclei of interest (¹H, ¹³C, ¹⁹F)
• Provide solvent preferences and sample goals

2. Sample Preparation

Dissolution in deuterated solvents
• Filtration (if needed)

3. NMR Measurement

1D (proton, carbon) scans
• 2D NMR (COSY, HSQC, HMBC)
• Quantitative NMR (qNMR)

4. Data Processing & Reporting

Annotated spectra
• Peak assignments
• Structural interpretation
• Purity assessment

Why Choose Materials Metric for Your NMR Analysis

Materials Metric provides high-quality NMR analysis supported by extensive chemical, polymer, and biomolecular expertise.
Our NMR capabilities include:

¹H, ¹³C, and ¹⁹F NMR for a wide range of materials
Advanced 2D NMR studies for structural confirmation
Quantitative and qualitative insights for polymers, pharmaceuticals, and biomaterials
Identification of impurities, residual monomers, and degradation products
Clear, annotated reports tailored to your experimental or product development needs

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