Spectroscopic & Chemical Analysis

Spectroscopic and chemical analysis are fundamental to understanding composition, bonding, and molecular structure in materials and biological systems. These techniques provide definitive insight into chemical identity, functional groups, elemental composition, and interaction mechanisms that govern performance, stability, and safety. At Materials Metric, we integrate complementary spectroscopic and chemical analysis techniques to generate robust, interpretable chemical fingerprints across polymers, biomaterials, pharmaceuticals, coatings, composites, and advanced materials. Our workflows support materials development, quality control, failure investigation, and regulatory documentation by delivering precise, reproducible, and defensible chemical data aligned with research and commercialization needs.

Fluorescence Spectroscopy

Fluorescence Spectroscopy measures emission from excited molecules, enabling sensitive detection of fluorophores, conjugates, trace species, and biomolecular interactions. Materials Metric provides high-sensitivity fluorescence analysis for polymers, biological samples, coatings, and chemical formulations.

Nuclear Magnetic Resonance (NMR) Spectroscopy

NMR Spectroscopy delivers atomic-level structural information for organic molecules, polymers, and biomaterials using ¹H, ¹³C, ¹⁹F, and advanced 2D methods. Materials Metric offers high-resolution NMR analysis to confirm chemical structure, purity, degradation pathways, and molecular composition.

High-Performance Liquid Chromatography (HPLC)

HPLC separates, identifies, and quantifies chemical components in liquid samples with high precision. Materials Metric provides robust HPLC analysis for polymers, degradation products, pharmaceuticals, biomolecules, extractables/leachables, and formulation stability studies.

Gas Chromatography–Mass Spectrometry (GC–MS)

GC–MS combines gas-phase separation with mass spectral identification to detect volatile and semi-volatile compounds at trace levels. Materials Metric offers GC–MS testing for chemical purity, contamination analysis, residual solvents, polymer additives, and organic compound identification.

Atomic Absorption Spectroscopy (AAS)

AAS quantifies metal ions and trace elements by measuring light absorbed by vaporized atoms. Materials Metric provides sensitive elemental analysis for environmental samples, biomaterials, pharmaceuticals, coatings, and chemical formulations.

Inductively Coupled Plasma (ICP–OES / ICP–MS)

ICP enables multi-element quantification at parts-per-million to parts-per-billion sensitivity using optical emission (OES) or mass spectrometry (MS). Materials Metric offers ICP-based trace metal analysis for biomaterials, pharmaceuticals, polymers, coatings, and contamination assessment.

X-ray Diffraction (XRD)

XRD determines crystalline structure, phase composition, lattice parameters, and crystallite size of solid materials. Materials Metric provides high-quality XRD characterization for polymers, metals, ceramics, biomaterials, composites, and powdered samples.

X-ray Absorption Spectroscopy (XAS)

X-ray Absorption Spectroscopy (XAS) provides element-specific information on oxidation states, local atomic coordination, and bonding environments using XANES and EXAFS analysis. Materials Metric offers high-resolution XAS characterization for metals, ceramics, catalysts, battery materials, polymers, and advanced composites requiring nanoscale structural insight.

X-ray Photoelectron Spectroscopy (XPS)

XPS measures surface chemistry and electronic structure by analyzing photoemitted electrons from the top 5–10 nm of a material. Materials Metric offers XPS for elemental composition, oxidation states, chemical bonding, and surface modifications in coatings, films, and advanced materials.

X-ray Fluorescence (XRF) Spectroscopy

XRF provides non-destructive elemental analysis for bulk materials and thin films using characteristic X-ray emission. Materials Metric offers XRF for metals, ceramics, composites, coatings, polymers, and raw materials requiring rapid composition verification.

Raman Spectroscopy

Raman Spectroscopy provides molecular and structural information by measuring vibrational energy shifts in scattered light. Materials Metric offers high-resolution Raman analysis for polymers, biomaterials, nanomaterials, thin films, pharmaceuticals, and advanced composites requiring chemical, crystallinity, and phase characterization.

UV–Visible Spectroscopy (UV–Vis)

UV–Visible Spectroscopy is an analytical technique that measures how molecules absorb light in the ultraviolet and visible wavelength range. Because absorbance is directly related to molecular structure, concentration, and electronic transitions, UV–Vis provides rapid, non-destructive insights into purity, stability, reaction kinetics, material changes, and functional behavior in liquid or solid samples.

To learn more about our Spectroscopic & Chemical Analysis, please contact us.

Frequently Asked Questions

What are spectroscopic analysis services?

Spectroscopic analysis services use the interaction of light, X-rays, or magnetic fields with matter to identify materials, determine composition, and measure chemical and physical properties. They span molecular techniques such as NMR, Raman, UV-Vis, and fluorescence and elemental techniques such as AAS, ICP, XRF, and XPS. Materials Metric selects the right method or combination for each question.

What can spectroscopic analysis determine?

These services identify unknown materials, confirm structure and identity, quantify elements and compounds, and characterize surfaces, oxidation states, and optical or electronic properties. They support composition verification, impurity and contaminant analysis, and failure investigation. Choosing complementary methods often gives a more complete picture than any single technique.

What sample is required for spectroscopic analysis?

Solids, powders, liquids, films, and digests can all be accommodated, and requirements vary by technique from a few milligrams to a few milliliters. Some methods are non-destructive with little preparation, while elemental methods often need digestion or dissolution. Materials Metric advises on sample amount and preparation once the goal is defined.

Which standards apply to spectroscopic analysis?

Materials Metric uses validated or fit-for-purpose methods aligned with ASTM/ISO and relevant pharmacopeial guidance where applicable, with specific standards such as USP <232>/<233> and ICH Q3D applied for elemental impurities. Calibration against traceable reference materials underpins accuracy across methods. The applicable standard is confirmed for each technique and intended use.