Nuclear Magnetic Resonance (NMR) Spectroscopy
Nuclear Magnetic Resonance (NMR) Spectroscopy is a powerful analytical technique that uses magnetic fields and radiofrequency signals to determine molecular structure, purity, and chemical environment. By observing how atomic nuclei respond to magnetic excitation, NMR provides detailed information about chemical bonds, functional groups, molecular connectivity, and conformation.
Materials Metric supports multiple NMR nuclei including ¹H (proton), ¹³C (carbon), and ¹⁹F, along with advanced 2D experiments such as COSY, HSQC, and HMBC for in-depth structural elucidation of polymers, organic compounds, and biomolecules.
Use of NMR Spectroscopy
NMR is used to:
• Determine molecular structure and connectivity
• Confirm polymer composition and branching
• Identify impurities, degradation products, and side reactions
• Measure monomer ratios, functional group conversions, and end groups
• Evaluate biomolecules including peptides, metabolites, and natural compounds
Applications of NMR Spectroscopy
• Polymers: composition, crosslinking, additive identification
• Pharmaceuticals: purity, identity, stability testing
• Biomaterials: polymer chemistry and functionalization
• Organic Synthesis: structure verification and reaction monitoring
• Natural Products: metabolite and compound identification
Sample Analysis Process
1. Submission & Review
- Identify nuclei of interest (¹H, ¹³C, ¹⁹F)
- Provide solvent preferences and sample goals
2. Sample Preparation
- Dissolution in deuterated solvents
- Filtration (if needed)
3. NMR Measurement
- 1D (proton, carbon) scans
- 2D NMR (COSY, HSQC, HMBC)
- Quantitative NMR (qNMR)
4. Data Processing & Reporting
- Annotated spectra
- Peak assignments
- Structural interpretation
- Purity assessment
Why Choose Materials Metric for Your NMR Analysis
Materials Metric provides high-quality NMR analysis supported by extensive chemical, polymer, and biomolecular expertise.
Our NMR capabilities include:
- ¹H, ¹³C, and ¹⁹F NMR for a wide range of materials
- Advanced 2D NMR studies for structural confirmation
- Quantitative and qualitative insights for polymers, pharmaceuticals, and biomaterials
- Identification of impurities, residual monomers, and degradation products
- Clear, annotated reports tailored to your experimental or product development needs
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