Publications and Case Studies
Repurposing Biowaste for Biomedical Applications: Eggshell containing Injectable Bone Substitution Cements for Bone Regeneration
This peer-reviewed study reviews how eggshell-derived biowaste can be repurposed as a bioactive additive in injectable bone substitution cements to overcome limitations of conventional grafts and synthetic cements. By leveraging the calcium carbonate–rich composition and trace elements naturally present in eggshells, the work demonstrates a sustainable approach to enhancing bioactivity while maintaining the mechanical strength and injectability required for bone regeneration applications.
Advancements in hydroxyapatite synthesis and surface modifications for emerging biomedical applications
This peer-reviewed review synthesizes recent advances in hydroxyapatite (HA) synthesis and surface modification, highlighting how traditional and emerging fabrication routes—including bio-derived sources—are expanding HA’s biomedical potential. By examining controlled synthesis strategies, chemical substitutions, and surface functionalization approaches, the study outlines how tailored HA systems improve performance in bone, dental, drug-delivery, and regenerative applications while identifying key challenges and future directions for clinical translation.
Evaluating the advancements in a recently introduced universal adhesive compared to its predecessor
This study rigorously compares a newly upgraded universal dental adhesive with its predecessor, focusing on dentin bonding performance and key physicomechanical properties. While both adhesives demonstrated comparable bond strength and survival probability across application modes, the newer formulation exhibited improved material characteristics—lower viscosity, thinner adhesive layer, higher hardness, elastic modulus, and degree of conversion—highlighting how formulation updates can enhance handling and mechanical behavior without compromising clinical bonding efficacy.
Optimizing alkaline hydrothermal treatment for biomimetic smart metallic orthopedic and dental implants
In this research study, we investigated a biomimetic surface engineering strategy for titanium orthopedic and dental implants using alkaline hydrothermal treatment inspired by cicada wing nanostructures. The engineered nanotextured surfaces significantly improved wettability, osteoblast adhesion, and cell viability while simultaneously reducing bacterial risk—addressing two critical challenges in implant failure. The findings demonstrate strong potential for translating nanostructured, bioinspired implant surfaces into next-generation orthopedic and dental applications that enhance osseointegration and long-term clinical performance
Surface modification of Polyether-ether-ketone for enhanced cell response: a chemical etching approach
This original research investigates a chemical etching strategy to transform bioinert polyether-ether-ketone (PEEK) into a nano-porous, cell-responsive biomaterial for orthopedic and dental applications. By systematically applying sulfuric acid etching followed by different post-treatments, the study demonstrates significant improvements in surface roughness, wettability, osteoblastic cell viability, and alkaline phosphatase activity compared to untreated PEEK. The findings show that tailored surface chemistry and nanoscale porosity can substantially enhance PEEK’s osteogenic potential, supporting its broader use as a metal-free implant material.